Dallas Buyers Club

Most actors try their best with every role they take on, but then there's that rare opportunity that requires a physical transformation into the character, and Matthew McConaughey and Jared Leto take on the challenge by taking off nearly 80 pounds between the two of them. The former plays a homophobic rodeo cowboy and electrician, the latter plays a transgender drug-addict; together, they set their differences aside to build and operate an underground pharmaceutical market to treat others livings with AIDS just like them. McConaughey and Leto rightfully took home Oscars for their performances. Garner, O'Hare and Zahn work out nicely in supporting roles. Also won Best Makeup & Hairstyling, and nominated for Best Picture, Best Original Screenplay and Best Editing.